Key Takeaways
Cadence, a clinical AI company, raised a $100 million Series C led by Spark Capital at a $1.23 billion valuation.
The company uses AI care agents to manage chronic disease for older adults across more than 20 health systems and 100,000 active patients.
Cadence says its model saves Medicare about $2.7 million every week as a clinician shortage deepens.
Cadence, a clinical AI company that manages chronic care for older adults, raised a $100 million Series C led by Spark Capital, the company announced on June 23, 2026. The round, reported by STAT and Business Wire, values Cadence at about $1.23 billion.
Thrive Capital, General Catalyst, Coatue, B Capital, and the venture arms of health systems Corewell Health and Memorial Hermann joined the round, along with Duke Health. Cadence works with more than 20 health systems and treats over 100,000 active patients, using AI agents to monitor blood pressure, diabetes, and other chronic conditions between doctor visits.
Chronic conditions like heart failure, hypertension, and type 2 diabetes drive a large share of US health spending, and they require steady monitoring that overworked practices struggle to provide. Cadence's pitch is that AI agents can handle routine check-ins, flag patients who are slipping, and route urgent cases to human clinicians, keeping more people stable at home and out of the hospital.
The company says its model saves Medicare roughly $2.7 million every week. The funding targets a widening gap. About 56 million older adults live with chronic disease in the United States, and the supply of clinicians to manage them is not keeping pace. Cadence also announced new affiliations with Duke Health and Texas Health Resources, one of the largest nonprofit systems in North Texas.
Cadence describes the AI as regulated and designed to work alongside clinicians rather than replace them. The bet fits a broader pattern of capital flowing toward machines that fill human gaps, from robots moving into food, farming, and care to longevity startups like NewLimit. The most notable part is who is buying in, the hospitals themselves.
People Also Ask
What does Cadence do?
Cadence is a clinical AI company that manages chronic conditions like hypertension and diabetes for older adults, using AI care agents that work with more than 20 health systems.
How much did Cadence raise in its Series C?
Cadence raised $100 million in a Series C led by Spark Capital, reaching a valuation of about $1.23 billion.
How does AI chronic care save Medicare money?
Cadence says its model saves Medicare roughly $2.7 million every week by monitoring patients between visits and preventing costly hospitalizations.
Who invested in Cadence's Series C?
Spark Capital led the round, with Thrive Capital, General Catalyst, Coatue, B Capital, Corewell Health Ventures, Memorial Hermann, and Duke Health participating.